RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
IGF1
RNA ID
RNA Type
mRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
ELISA; Immunofluorescence; RT-PCR etc.
Target
NA
Pathway
IGF1 SIGNALING PATHWAY
PubMed ID
Title
Regulation of the IGF1 signaling pathway is involved in idiopathic pulmonary fibrosis induced by alveolar epithelial cell senescence and core fucosylation
Year
2021
Function
"Western blotting showed that the levels of IGF1, IGFR-1, PI3K, AKT and p-AKT in lung tissues of patients with IPF were significantly higher than those in normal lung tissues. This indicated that the IGF1 signaling pathway is activated in IPF conditions."